The 2009 schedule just came out:
Open with a four game series in St. Louis while the home opener is against the Astros.
Play in Chicago for 6 games in late May. Indians come to PNC Park in late June which will hopefully get some good attention and maybe spark some emotions.
No tough period really sticks out to me, seems to be a pretty even schedule overall but still can't really tell until the other teams start playing.