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Series preview: Pirates host Cubs in four-game set

For the final time in 2022, the Pirates face the Cubs.

Chicago Cubs v Pittsburgh Pirates Photo by Justin Berl/Getty Images

Chicago Cubs vs. Pittsburgh Pirates, September 22-25, 2022

Location: PNC Park, Pittsburgh, PA

TV: AT&T Sports Pittsburgh

Radio: KDKA-AM

Cubs SB Nation Site: Bleed Cubbie Blue

The Pirates play in Pittsburgh for the final time this season, hosting a four-game set against the Cubs.

Here’s a look at what we can expect:

Projected Starters

Thursday, 6:35 p.m. EST

Hayden Wesneski vs. Mitch Keller

Friday, 6:35 p.m. EST

Javier Assad vs. Bryse Wilson

Saturday, 6:35 p.m. EST

Wade Miley vs. Johan Oviedo

Sunday, 1:35 p.m. EST

Adrian Sampson vs. Luis Ortiz

Projected Lineups


  1. Zach McKinstry (L) 2B
  2. Ian Happ (S) LF
  3. Yan Gomes (R) C
  4. Franmil Reyes (R) DH
  5. P.J. Higgins (R) 1B
  6. David Bote (R) 3B
  7. Nelson Velazquez (R) RF
  8. Michael Hermosillo (R) CF
  9. Christopher Morel (R) SS


  1. Oneil Cruz (L) SS
  2. Bryan Reynolds (S) CF
  3. Rodolfo Castro (S) 2B
  4. Ben Gamel (L) RF
  5. Ke’Bryan Hayes (R) 3B
  6. Cal Mitchell (L) DH
  7. Jack Suwinski (L) LF
  8. Zack Collins (L) 1B
  9. Jason Delay (R) C